PTx is devoted to developing and commercializing cancer medicines and combination therapies that can make a meaningful difference in the lives of cancer patients. We are united in our passion for improving the treatment of cancer and our desire to make a meaningful contribution to outcomes. We believe that innovation is not enough. In today’s challenging healthcare climate, we strive to develop and assess our products based on the real-world impact they have in improving the quality and duration of our patients’ lives. We measure our success in the birthdays, anniversaries, and other important life moments that our patients are able to enjoy.


PTx has recently acquired global rights to Leukine (Sargramostim). Leukine is the only licensed FDA-approved GM-CSF, and PTx is investing in Leukine to position it for growth. With Leukine, PTx acquired its state-of-the-art manufacturing facility in Lynnwood and we are North of Seattle, just a few minutes from downtown (but far enough out of, traffic and high cost of living in the city!). We are an established team with a renewed energy to seize on an exciting opportunity. To get there we need outstanding people to join our team of talented, innovative and committed professionals.


The Downstream Process Science Group is composed of Scientists and Subject Matter Experts who are responsible for the development, maintenance and remediation of the Production downstream process. This position requires downstream development, optimization and characterization studies using small-scale models and analysis and interpretation of experimental data.



  • Supports downstream purification efforts in the development and manufacturing areas.

  • Conducts laboratory experiments related to development and product characterization.

  • Interprets results to make process improvements and design future studies.

  • Provides scientific technical support to the cGMP manufacturing group.

  • Communicates work through presentations and written documentation.

  • Set-up, maintenance and operation of HPLC’s (semi preparative and analytical)

  • Design, execute and interpret small scale drug product stability studies.

  • Process and analyze experimental data using established analytical techniques.

  • Familiarity with semi prep and prep chromatography as well as use of membrane​


*This role currently has no direct reports to manage, but they must embody leadership skills to be successful (including effective intrapersonal and cross-functional communications both written and verbal, relationship building, agility and adaptability.


*Key responsibilities may differ among employees with the same job title and may change over time, in accordance with business needs


  • Bachelor's Degree in Science or Engineering and 5-10 years working in Process  Development for biologics



  • Demonstrated strong organizational, interpersonal and project management skills

  • Expertise with HPLC, SDS-PAGE and other routine analytical methods

  • Ability to work independently

  • Strong writing skills and oral presentation skills

  • Familiarity with ICH and FDA Guidelines

  • Experience with peptide mapping and LC/MS desirable


Compensation and benefits are very competitive. They include a base salary, performance bonus, stock options and profit sharing. Our benefits include health, vision, dental and life Ins, 401(k) with match & PTO


To be considered for the position, please send your resume to


(781) 218-9394


19 Muzzey Street

Lexington, MA 02421

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© 2017 Partner Therapeutics, Inc.