PTx is devoted to developing and commercializing cancer medicines and combination therapies that can make a meaningful difference in the lives of cancer patients. We are united in our passion for improving the treatment of cancer and our desire to make a meaningful contribution to outcomes. We believe that innovation is not enough. In today’s challenging healthcare climate, we strive to develop and assess our products based on the real-world impact they have in improving the quality and duration of our patients’ lives. We measure our success in the birthdays, anniversaries, and other important life moments that our patients are able to enjoy.


PTx has recently acquired global rights to Leukine (Sargramostim). Leukine is the only licensed FDA-approved GM-CSF, and PTx is investing in Leukine to position it for growth. With Leukine, PTx acquired its state-of-the-art manufacturing facility in Lynnwood and we are North of Seattle, just a few minutes from downtown (but far enough out of, traffic and high cost of living in the city!). We are an established team with a renewed energy to seize on an exciting opportunity. To get there we need outstanding people to join our team of talented, innovative and committed professionals.


The Upstream Process Science Department is a group of Scientists and Subject Matter Experts who specialize in the development, maintenance, remediation and transfer of the production processes used in cGMP commercial manufacturing.  This position requires hands-on execution of upstream development, optimization and characterization experiments using small-scale models, then analysis and interpretation of experimental data.



  • Supports upstream fermentation efforts in the development and manufacturing areas.

  • Conduct laboratory experiments related to development, scale-up and characterization of fermentation and primary recovery processes.

  • Interpret results to make process improvements and further design next studies.

  • Provides upstream technical support for cGMP manufacturing.

  • Provides scientific technical support for technology transfer of processes to manufacturing.

  • Communicates work through oral presentations and written documentation including technical reports, qualification reports and GMP documents.

  • Set-up, maintenance and operation of bioprocessing equipment including shake flasks, fermenters and tangential flow filtration equipment.

  • Preparation of media and buffers.

  • Process and analyze experimental data.



  • PTx’s leaders are effective operating in an evolving, complex and dynamic environment.  They provide clear direction and instruction to supervisors, direct reports and teams and continuously identify internal and external best practices and opportunities for improvement.


  • PTx’s leaders understand patient and customer needs and build goals and relationships to ensure their needs and site goals are both met.  They create a vision for the organization while continuously improving operations through team’s accountability to high performance standards.



  • BS/BE Degree; Biological Sciences, Biochemistry, Chemistry, Engineering.

    • Five to ten years of experience in Process Development.

  • MS Degree; Biological Sciences, Biochemistry, Chemistry, Engineering.

    • Four to eight years of experience in Process Development.

  • Experience with typical fermentation/cell culture operations and recovery processes, including shake flask expansion, small and large scale fermenter/bioreactor production, scale-up/scale-down, process transfer, and tangential flow filtration (TFF).



  • Detail- oriented with the ability to work with minimal supervision, and complete written and verbally assigned tasks following specific procedures.

  • Ability to independently make decisions based on data, scientific knowledge and sound judgement

  • Knowledge of Design of Experiments (DOE) and statistical data analysis

  • Ability to work in a clean room environment with proper aseptic technique.

  • Excellent communication skills both written and oral external partners on significant matters often requiring coordination across facility locations.


Compensation and benefits are very competitive. They include a base salary, performance bonus, stock options and profit sharing. Our benefits include health, vision, dental and life INS, 401(k) with match & PTO


To be considered for the position, please send your resume to


(781) 218-9394


19 Muzzey Street

Lexington, MA 02421

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© 2017 Partner Therapeutics, Inc.